Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145249 | 0.93 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2FDPSLMNAHSD17B10 | |
| SCHEMBL2244380 | 0.90 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Water SCHEMBL3307857 | 0.87 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3431851 | 0.85 | MEN1 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7921722 | 0.85 | FDPS (0.39) | ALDH1A1FDPSMEN1KMT2ATSHR | |
| SCHEMBL1403832 | 0.83 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2FDPSLMNAHSD17B10 | |
| SCHEMBL865701 | 0.82 | FDPS (0.36) | ALDH1A1FDPSLMNATSHRKCNA5 | |
| SCHEMBL2242804 | 0.82 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL1686729 | 0.82 | FDPS (0.42) | FDPSMEN1KMT2AKCNA5 | |
| SCHEMBL7933576 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097297-A1 | PYRIDO[3, 4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2018-05-31 | — | — | WO | disclosed |