Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 8/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK7 | P50613 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203637 | 0.87 | ENPP2 (0.43) | MEN1KMT2AHSP90AA1ALDH1A1TSHR | |
| SCHEMBL20203582 | 0.85 | KDR (0.40) | MEN1HSP90AA1ALDH1A1TSHRCDK1 | |
| SCHEMBL23733468 | 0.85 | NPC1 (0.42) | HSP90AA1ALDH1A1CDK1CDK4CDK2 | |
| SCHEMBL20203642 | 0.84 | CDK4 (0.47) | HSP90AA1ALDH1A1TSHRCDK1CDK4 | |
| SCHEMBL20203603 | 0.84 | CDK1 (0.46) | CYP2C19HSP90AA1ALDH1A1CDK1CDK4 | |
| SCHEMBL23733491 | 0.84 | CYP2C19 (0.38) | GABRG2GABRB3GABRA5KCNH2CYP2C19 | |
| SCHEMBL20203594 | 0.82 | TLR9 (0.39) | GABRG2GABRB3GABRA5KCNH2CYP2C19 | |
| SCHEMBL20203592 | 0.82 | ALDH1A1 (0.45) | CYP2C19MEN1KMT2AHSP90AA1ALDH1A1 | |
| SCHEMBL18806180 | 0.82 | CDK1 (0.44) | GABRG2GABRB3GABRA5KCNH2MEN1 | |
| SCHEMBL20203586 | 0.82 | ALDH1A1 (0.37) | GABRG2GABRB3GABRA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084814-B2 | Pyrido[3, 4-d]pyrimidine derivative and pharmaceutically acceptable salt thereof | TEIJIN PHARMA LIMITED (JP) | 2021-08-10 | — | — | US | disclosed |
| WO-2018097297-A1 | PYRIDO[3, 4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084814-B2 | Pyrido[3, 4-d]pyrimidine derivative and pharmaceutically acceptable salt thereof | CDK4, CDK6, CDK16 | GABRG2 4149/4885GABRB3 4474/4885GABRA5 4019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.