Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTR1B | P28222 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 11/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1F | P30939 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016008 | 0.87 | KMT2A (0.65) | KMT2AHTR1BHTR1AHTR1DMEN1 | |
| SCHEMBL2045339 | 0.86 | KMT2A (0.45) | KMT2AHTR1BHTR1AHTR1DMEN1 | |
| SCHEMBL12574208 | 0.85 | KMT2A (0.69) | KMT2AHTR1BHTR1AHTR1DMEN1 | |
| SCHEMBL2020894 | 0.85 | HTR1B (0.56) | KMT2AHTR1BHTR1AHTR1DMEN1 | |
| SCHEMBL2018573 | 0.85 | KMT2A (0.69) | KMT2AHTR1BHTR1AHTR1DMEN1 | |
| SCHEMBL12574206 | 0.85 | KMT2A (0.69) | KMT2AHTR1BHTR1AHTR1DMEN1 | |
| SCHEMBL2020998 | 0.85 | CNR1 (0.49) | KMT2AHTR1BHTR1AHTR1DMEN1 | |
| SCHEMBL2018448 | 0.82 | CNR1 (0.60) | HTR1BHTR1AHTR1DCNR1CNR2 | |
| SCHEMBL2017142 | 0.81 | CNR1 (0.68) | HTR1BHTR1AHTR1DCNR1CNR2 | |
| SCHEMBL2045340 | 0.77 | HTR1B (0.48) | KMT2AHTR1BHTR1AHTR1DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160180-A1 | Cannabinoid Receptor Ligands | ASTRAZENECA AB (SE) | 2011-06-30 | — | — | US | disclosed |
| US-20090062251-A1 | Novel Compounds 002 | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062251-A1 | Novel Compounds 002 | OPRL1, OPRK1, OPRM1 | KMT2A 2567/4885HTR1B 269/4885HTR1A 444/4885 |
| US-20110160180-A1 | Cannabinoid Receptor Ligands | CNR1, CNR2, OPRL1 | KMT2A 2050/4885HTR1B 159/4885HTR1A 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.