Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 4/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208043 | 0.90 | TACR1 (0.34) | CHRM3KCNH2 | |
| SCHEMBL13351513 | 0.77 | GABRA1 (0.35) | HTR1D | |
| SCHEMBL22861056 | 0.75 | NPC1 (0.40) | KCNH2HTR1D | |
| SCHEMBL22043094 | 0.75 | MAOB (0.33) | MAOBMAOA | |
| SCHEMBL8904980 | 0.75 | MAOB (0.36) | MAOBMAOANOS1 | |
| SCHEMBL8110112 | 0.75 | MAOB (0.36) | MAOBMAOANOS1 | |
| SCHEMBL9224226 | 0.75 | MEN1 (0.38) | MAOBMAOA | |
| SCHEMBL8110108 | 0.75 | MAOB (0.36) | MAOBMAOANOS1 | |
| SCHEMBL9224228 | 0.75 | MEN1 (0.38) | MAOBMAOA | |
| SCHEMBL8736719 | 0.75 | MAOB (0.36) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |