Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | INMT | O95050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961031 | 0.81 | CRBN (0.52) | CRBNDDB1GAAGRM5MEN1 | |
| SCHEMBL14401319 | 0.79 | — | — | |
| SCHEMBL14075354 | 0.74 | CRBN (0.39) | CRBNDDB1GAAGRM5MEN1 | |
| SCHEMBL20204883 | 0.72 | — | — | |
| SCHEMBL11599999 | 0.69 | CRBN (0.49) | CRBNDDB1GAAGRM5MEN1 | |
| SCHEMBL14218693 | 0.68 | EPHX2 (0.51) | CRBNDDB1GAAALDH1A1KMT2A | |
| SCHEMBL508107 | 0.68 | — | — | |
| SCHEMBL20206746 | 0.68 | CRBN (0.33) | CRBNDDB1 | |
| SCHEMBL11568357 | 0.67 | CRBN (0.55) | CRBNDDB1GAAMEN1ALDH1A1 | |
| SCHEMBL13501654 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |