⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182138 | 0.78 | — | — | |
| SCHEMBL13283961 | 0.76 | — | — | |
| SCHEMBL23323359 | 0.73 | — | — | |
| SCHEMBL7323960 | 0.73 | — | — | |
| SCHEMBL20206746 | 0.72 | CRBN (0.33) | — | |
| SCHEMBL20204675 | 0.72 | CRBN (0.40) | — | |
| SCHEMBL10203979 | 0.70 | — | — | |
| SCHEMBL15829241 | 0.70 | CRBN (0.37) | — | |
| SCHEMBL2917333 | 0.65 | CRBN (0.46) | — | |
| SCHEMBL2919526 | 0.64 | BRD4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293524-A1 | OTIC FORMULATIONS FOR DRUG-INDUCED OTOTOXICITY | SPIRAL THERAPEUTICS INC. | 2023-09-21 | — | — | US | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |