SCHEMBL20206746

SCHEMBL20206746

C=C1NC(=O)CCN1C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 5/20 0.33
DDB1 Q16531 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19370324 0.81 CRBN (0.38) CRBNDDB1
SCHEMBL24519704 0.79 CRBN (0.38) CRBN
SCHEMBL20206744 0.77
SCHEMBL21325192 0.76 CRBN (0.33) CRBNDDB1
SCHEMBL17930247 0.73
SCHEMBL20204883 0.72
SCHEMBL14192102 0.68 DDB1 (0.46) CRBNDDB1
SCHEMBL508833 0.68 CNR1 (0.33)
SCHEMBL20204675 0.68 CRBN (0.40) CRBNDDB1
SCHEMBL22414473 0.67 CRBN (0.35) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018098204-A1 6-MEMBERED URACIL ISOSTERES CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed