Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319580 | 0.86 | — | — | |
| SCHEMBL17224690 | 0.77 | ACE (0.38) | — | |
| SCHEMBL1106524 | 0.76 | SMN1; SMN2 (0.37) | JAK2 | |
| SCHEMBL17234124 | 0.75 | RAB9A (0.37) | — | |
| SCHEMBL6609022 | 0.74 | MEN1 (0.33) | JAK2 | |
| SCHEMBL18603274 | 0.72 | MEN1 (0.32) | — | |
| SCHEMBL18183405 | 0.72 | MEN1 (0.32) | — | |
| SCHEMBL17234137 | 0.70 | LMNA (0.40) | — | |
| SCHEMBL7627883 | 0.70 | — | — | |
| SCHEMBL13501646 | 0.70 | KDM4E (0.36) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |