Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 11/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21324997 | 0.93 | DUT (0.51) | DUTIDO1TDO2RIPK1GRM2 | |
| SCHEMBL20188353 | 0.92 | DUT (0.50) | DUTIDO1TDO2GRM2ROCK2 | |
| SCHEMBL21315522 | 0.92 | DUT (0.50) | DUTIDO1TDO2GRM2ROCK2 | |
| SCHEMBL13539468 | 0.90 | DUT (0.55) | DUTIDO1TDO2ROCK2 | |
| SCHEMBL29387080 | 0.88 | DUT (0.54) | DUT | |
| SCHEMBL16891348 | 0.88 | DUT (0.46) | DUTIDO1TDO2RIPK1GRM2 | |
| SCHEMBL29363809 | 0.87 | DUT (0.47) | DUTIDO1TDO2GRM2ROCK2 | |
| SCHEMBL15864646 | 0.87 | DUT (0.47) | DUTIDO1TDO2GRM2ROCK2 | |
| SCHEMBL17492963 | 0.87 | DUT (0.47) | DUTIDO1TDO2GRM2ROCK2 | |
| SCHEMBL20191222 | 0.86 | DUT (0.52) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |