Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 7/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204783 | 0.88 | DUT (0.53) | DUTRIPK1IDO1TDO2GRM2 | |
| SCHEMBL21325251 | 0.87 | DUT (0.45) | DUTRIPK1IDO1TDO2GRM2 | |
| SCHEMBL20188354 | 0.87 | DUT (0.43) | DUTRIPK1IDO1TDO2GRM2 | |
| SCHEMBL22414494 | 0.86 | DUT (0.45) | DUTRIPK1IDO1TDO2GRM2 | |
| SCHEMBL20347946 | 0.84 | DUT (0.46) | DUTRIPK1IDO1TDO2GRM2 | |
| SCHEMBL21324997 | 0.84 | DUT (0.51) | DUTRIPK1IDO1TDO2GRM2 | |
| SCHEMBL21315522 | 0.83 | DUT (0.50) | DUTIDO1TDO2GRM2HTR2A | |
| SCHEMBL20188353 | 0.83 | DUT (0.50) | DUTIDO1TDO2GRM2HTR2A | |
| SCHEMBL12696881 | 0.82 | DUT (0.44) | DUTRIPK1IDO1TDO2GRM2 | |
| SCHEMBL15864648 | 0.82 | DUT (0.39) | DUTRIPK1IDO1TDO2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103489-A1 | HETEROATOM CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-07-09 | — | — | WO | disclosed |