Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25261825 | 0.76 | TLR4 (0.48) | TLR4TLR2PARP15PARP10 | |
| SCHEMBL2208421 | 0.74 | TLR4 (0.46) | TLR4TLR2PARP15PARP10 | |
| SCHEMBL29818744 | 0.74 | TLR4 (0.46) | TLR4TLR2PARP15PARP10 | |
| SCHEMBL4568816 | 0.74 | TLR4 (0.46) | TLR4TLR2PARP15PARP10 | |
| SCHEMBL21035308 | 0.73 | PARP10 (0.51) | PARP15PARP10 | |
| SCHEMBL20204689 | 0.73 | SLC6A4 (0.38) | SLC6A2SLC6A4KCNH2ACACB | |
| SCHEMBL12647108 | 0.71 | TLR4 (0.49) | TLR4TLR2ALDH1A1TP53CYP3A4 | |
| SCHEMBL13798779 | 0.71 | CHRNB4 (0.60) | TLR4TLR2ALDH1A1TP53CYP3A4 | |
| SCHEMBL16902845 | 0.71 | CHRNB4 (0.66) | TLR4TLR2NR1H4 | |
| SCHEMBL931640 | 0.71 | MAOB (0.53) | TLR4TLR2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |