Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | CEL | P19835 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204601 | 0.94 | CYP2D6 (0.39) | CYP2D6CYP1A2CYP2C19MAOBMAOA | |
| SCHEMBL20207840 | 0.91 | CYP2D6 (0.42) | CYP2D6CYP1A2CYP2C19CELHSD17B10 | |
| SCHEMBL24019545 | 0.84 | HTR2A (0.42) | CYP2D6CYP1A2CYP2C19MAOBMAOA | |
| SCHEMBL20204830 | 0.84 | CYP2D6 (0.38) | CYP2D6CYP1A2CYP2C19CELHTR1D | |
| SCHEMBL20201909 | 0.81 | MAOB (0.38) | MAOBMAOAHTR2AHTR2CCEL | |
| SCHEMBL20207510 | 0.76 | CYP2D6 (0.40) | CYP2D6CYP1A2CYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL20204654 | 0.76 | CEL (0.41) | MAOBMAOAHTR2AHTR2CCEL | |
| SCHEMBL16191252 | 0.76 | HTR2C (0.45) | HTR2AHTR2CCEL | |
| SCHEMBL20208498 | 0.74 | MAOB (0.37) | MAOBMAOAHTR2AHTR2CCEL | |
| SCHEMBL20204607 | 0.73 | TYR (0.41) | CYP2D6CYP1A2CYP2C19HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |