Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KIF20A | O95235 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204792 | 0.84 | PBRM1 (0.48) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL20204958 | 0.83 | PBRM1 (0.57) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL20204839 | 0.82 | PBRM1 (0.51) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL20204843 | 0.82 | ALDH1A1 (0.46) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL6156793 | 0.77 | PBRM1 (0.58) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL13134166 | 0.77 | PBRM1 (0.67) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL27320955 | 0.77 | PBRM1 (0.67) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL5653872 | 0.76 | GPR84 (0.64) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL27762348 | 0.76 | GPR84 (0.64) | PBRM1GPR84KMT2AALDH1A1NR4A2 | |
| SCHEMBL245111 | 0.76 | GPR84 (0.65) | PBRM1GPR84KMT2AALDH1A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098473-A1 | REAGENTS AND METHODS FOR ANALYSIS OF PROTEINS AND METABOLITES TARGETED BY COVALENT PROBES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-31 | — | — | WO | disclosed |