Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | RORA | P35398 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536069 | 0.93 | ROCK2 (0.42) | HTR6DDB1CRBNBRD4PKM | |
| SCHEMBL20204818 | 0.83 | DUT (0.44) | HTR6DDB1CRBNBRD4 | |
| SCHEMBL21536738 | 0.83 | DUT (0.42) | DDB1CRBNBRD4PKMALDH1A1 | |
| SCHEMBL21536688 | 0.80 | DDB1 (0.44) | DDB1CRBNALDH1A1 | |
| SCHEMBL21536686 | 0.79 | DDB1 (0.43) | HTR6DDB1CRBNBRD4PKM | |
| SCHEMBL21536067 | 0.76 | DDB1 (0.46) | DDB1CRBNPKMALDH1A1 | |
| SCHEMBL21536613 | 0.74 | DUT (0.45) | DDB1CRBNBRD4PGRF2 | |
| SCHEMBL26029515 | 0.73 | DUT (0.41) | BRD4PKMALDH1A1PGRF2 | |
| SCHEMBL21536579 | 0.72 | DUT (0.47) | DDB1CRBNALDH1A1 | |
| SCHEMBL21536616 | 0.70 | DUT (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |