Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15252941 | 0.80 | HTR2A (0.42) | MAOBMAOAHTR2AHTR2CKDM1A | |
| SCHEMBL17997278 | 0.79 | HTR2A (0.44) | MAOBMAOAHTR2AHTR2CKDM1A | |
| SCHEMBL22170138 | 0.79 | MAOB (0.40) | MAOBMAOAHTR2AHTR2CSLC6A4 | |
| SCHEMBL18374089 | 0.79 | MAOB (0.40) | MAOBMAOAHTR2AHTR2CSLC6A4 | |
| SCHEMBL13464689 | 0.78 | CEL (0.44) | MAOBMAOAHTR2AHTR2CKDM1A | |
| SCHEMBL28027009 | 0.78 | HTR2A (0.43) | MAOBMAOAHTR2AHTR2CDPP4 | |
| SCHEMBL23052673 | 0.76 | MAOB (0.38) | MAOBMAOAHTR2AHTR2CSLC6A4 | |
| SCHEMBL20204601 | 0.76 | CYP2D6 (0.39) | MAOBMAOAHTR2AHTR2C | |
| SCHEMBL15554512 | 0.75 | DPP4 (0.39) | HTR2AKDM1AKDM1BDPP4POLB | |
| SCHEMBL5041752 | 0.75 | TAAR1 (0.50) | HTR2ADPP4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098208-A1 | NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |