Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148467 | 0.87 | HTR2A (0.56) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16191252 | 0.83 | HTR2C (0.45) | HTR2AHTR2CSLC6A4DPP4DPP7 | |
| SCHEMBL22201819 | 0.83 | HTR2A (0.52) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL28027637 | 0.80 | MAOA (0.55) | HTR2AHTR2CMAOBMAOA | |
| SCHEMBL23052673 | 0.79 | MAOB (0.38) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9247403 | 0.79 | RIPK1 (0.36) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9247410 | 0.79 | RIPK1 (0.36) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8154321 | 0.78 | HTR2A (0.53) | HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8146287 | 0.78 | HTR2A (0.43) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL18374089 | 0.78 | MAOB (0.40) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103805208-B | Dicyclohexyl ethylene group substituted diphenylamine alkynes liquid crystalline cpd and preparation method thereof | SHAANXI NORMAL UNIVERSITY (CN) | 2015-08-19 | — | — | CN | disclosed |