Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC14B | O60729 | 2/20 | 0.40 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205378 | 0.97 | CDC14B (0.38) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL20205320 | 0.95 | CDC14B (0.37) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL20205379 | 0.93 | CDC14B (0.35) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL20205331 | 0.93 | CDC14B (0.38) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL20205471 | 0.93 | CDC14B (0.40) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL20205741 | 0.93 | CDC14B (0.36) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL20205333 | 0.92 | PLA2G2A (0.36) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL22859773 | 0.92 | CDC14B (0.38) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL20205307 | 0.90 | CDC14B (0.39) | CDC14BCDC14APGRALKCYP1B1 | |
| SCHEMBL20205404 | 0.90 | PGR (0.36) | CDC14BCDC14APGRALKCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544985-B1 | BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| WO-2018095940-A1 | BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |