SCHEMBL20205568

SCHEMBL20205568

c1ccc2c(-c3ccc(-c4cc5oc6cc7c(cc6c5c5c4oc4ccccc45)oc4cc(-c5ccc(-c6cccc8ccccc68)cc5)c5oc6ccccc6c5c47)cc3)cccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
KDM4E B2RXH2 3/20 0.38
MCL1 Q07820 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
KMT2A Q03164 2/20 0.38
ACMSD Q8TDX5 1/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALPI P09923 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
CASP3 P42574 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
CASP7 P55210 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20205463 0.90 MAPT (0.40) ALOX5KDM4EMCL1L3MBTL1HSD17B10
SCHEMBL20205571 0.87 CDC14B (0.43) ALOX5KDM4EMCL1L3MBTL1HSD17B10
SCHEMBL20205597 0.87 CDC14B (0.45) ALOX5KDM4EMCL1L3MBTL1HSD17B10
SCHEMBL17945229 0.87 ALOX5 (0.39) ALOX5KDM4EMCL1L3MBTL1HSD17B10
SCHEMBL20210081 0.86 ALOX5 (0.35) ALOX5KDM4EMCL1L3MBTL1HSD17B10
SCHEMBL22908124 0.85 ABCG2 (0.37) ALOX5KDM4EL3MBTL1HSD17B10MEN1
SCHEMBL20205454 0.85 GPR84 (0.39) ALOX5KDM4EMCL1L3MBTL1HSD17B10
SCHEMBL20205474 0.84 TDP1 (0.43) ALOX5KDM4EMCL1L3MBTL1HSD17B10
SCHEMBL20205560 0.83 CDC14B (0.45) ALOX5KDM4EMCL1L3MBTL1HSD17B10
SCHEMBL20205595 0.83 CDC14B (0.42) ALOX5KDM4EMCL1L3MBTL1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11453680-B2 Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) MERCK PATENT GMBH (DE) 2022-09-27 US disclosed
EP-3544985-B1 BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2021-05-12 EP disclosed
WO-2018095940-A1 BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11453680-B2 Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) OCIAD2, OCIAD1, JUND ALOX5 354/4885KDM4E 3994/4885MCL1 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.