Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205597 | 0.87 | CDC14B (0.45) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20205560 | 0.86 | CDC14B (0.45) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20205595 | 0.86 | CDC14B (0.42) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20205463 | 0.84 | MAPT (0.40) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20205571 | 0.84 | CDC14B (0.43) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL24649907 | 0.83 | KDM4E (0.35) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20205456 | 0.83 | MAPT (0.44) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20205476 | 0.83 | ALOX5 (0.44) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20205706 | 0.81 | PLA2G2A (0.41) | MAPTMEN1KMT2AKDM4EHPGD | |
| SCHEMBL20205462 | 0.80 | MAOB (0.45) | MAPTMEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544985-B1 | BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| WO-2018095940-A1 | BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |