SCHEMBL20206205

SCHEMBL20206205

CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCC(=O)NCCC(C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCN)NC1=O

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 13/20 0.72
▸ MC1R Q01726 8/20 0.72
▸ MC5R P33032 3/20 0.54
▸ MC3R P41968 3/20 0.54
▸ IL23R Q5VWK5 2/20 0.52
▸ F12 P00748 2/20 0.51
▸ KDM1A O60341 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21392396 1.00 MC4R (0.72) MC4RMC1RMC5RMC3RIL23R
SCHEMBL12092723 1.00 MC4R (0.72) MC4RMC1RMC5RMC3RIL23R
SCHEMBL12657421 0.98 MC4R (0.70) MC4RMC1RMC5RMC3RIL23R
SCHEMBL22606181 0.98 MC4R (0.70) MC4RMC1RMC5RMC3RIL23R
SCHEMBL20206215 0.98 MC4R (0.70) MC4RMC1RMC5RMC3RIL23R
SCHEMBL22606182 0.98 MC4R (0.73) MC4RMC1RMC5RMC3RIL23R
SCHEMBL22606146 0.98 MC4R (0.73) MC4RMC1RMC5RMC3RIL23R
SCHEMBL12657870 0.98 MC4R (0.73) MC4RMC1RMC5RMC3RIL23R
SCHEMBL12657702 0.97 MC4R (0.70) MC4RMC1RMC5RMC3RIL23R
SCHEMBL20206179 0.97 MC4R (0.70) MC4RMC1RMC5RMC3RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711039-B2 Melanocortin receptor-specific peptide with C-terminal naphthylalanine PALATIN TECHNOLOGIES, INC. (US) 2020-07-14 — — US disclosed
US-20180148478-A1 Melanocortin Receptor-Specific Peptide with C-Terminal Naphthylalanine PALATIN TECHNOLOGIES INC (US) 2018-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711039-B2 Melanocortin receptor-specific peptide with C-terminal naphthylalanine MC1R, MC3R, MC4R MC4R 3/4885MC1R 1/4885MC5R 4/4885
US-20180148478-A1 Melanocortin Receptor-Specific Peptide with C-Terminal Naphthylalanine MC1R, MC3R, MC4R MC4R 3/4885MC1R 1/4885MC5R 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback