SCHEMBL21392396

CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCC(=O)NCC[C@@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)C(CCN)NC1=O

nearest known ligand 0.72

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	13/20	0.72

▸	MC1R	Q01726	8/20	0.72

▸	MC5R	P33032	3/20	0.54

▸	MC3R	P41968	3/20	0.54

▸	IL23R	Q5VWK5	2/20	0.52

▸	F12	P00748	2/20	0.51

▸	KDM1A	O60341	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12092723	1.00	MC4R (0.72)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL20206205	1.00	MC4R (0.72)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL12657421	0.98	MC4R (0.70)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL22606181	0.98	MC4R (0.70)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL20206215	0.98	MC4R (0.70)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL22606182	0.98	MC4R (0.73)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL22606146	0.98	MC4R (0.73)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL12657870	0.98	MC4R (0.73)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL12657702	0.97	MC4R (0.70)	MC4RMC1RMC5RMC3RIL23R
SCHEMBL20206179	0.97	MC4R (0.70)	MC4RMC1RMC5RMC3RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019183472-A1	MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDE FORMULATIONS AND METHODS FOR GASTROINTESTINAL TRACT-SPECIFIC DELIVERY	PALATIN TECHNOLOGIES, INC. (US)	2019-09-26	—	—	WO	disclosed