Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760444 | 0.95 | ALDH1A1 (0.33) | ALDH1A1TSHRTDP1 | |
| SCHEMBL17689586 | 0.85 | — | — | |
| SCHEMBL18973916 | 0.85 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL13467249 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL20976965 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL17634930 | 0.83 | — | — | |
| SCHEMBL21388515 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TSHRTDP1 | |
| SCHEMBL18973918 | 0.80 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL18794759 | 0.80 | — | — | |
| SCHEMBL13183444 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149058-B2 | Multi-functional chemical agents, and the method for protein modification | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2021-10-19 | — | — | US | disclosed |
| US-20210163526-A9 | Multi-Functional Chemical Agents, and the Method for Protein Modification | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2021-06-03 | — | — | US | disclosed |
| US-10682419-B2 | Prodrugs of peptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| EP-2525831-B1 | CARRIER-LINKED CARBAMATE PRODRUG LINKERS | ASCENDIS PHARMA AS (DK) | 2019-05-15 | — | — | EP | disclosed |
| EP-2616102-B1 | PRODRUGS COMPRISING AN EXENDIN LINKER CONJUGATE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2019-05-01 | — | — | EP | disclosed |
| US-20190085020-A1 | Multi-Functional Chemical Agents, and the Method for Protein Modification | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2019-03-21 | — | — | US | disclosed |
| US-20180147291-A1 | PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS | ONYX THERAPEUTICS, INC. | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147291-A1 | PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS | PREP, VIP, PEPD | ALDH1A1 1285/4885TSHR 3808/4885TDP1 2375/4885 |
| US-11149058-B2 | Multi-functional chemical agents, and the method for protein modification | FN1, LCP1, NPM1 | ALDH1A1 3553/4885TSHR 3371/4885TDP1 2808/4885 |
| US-20190085020-A1 | Multi-Functional Chemical Agents, and the Method for Protein Modification | FN1, LCP1, NPM1 | ALDH1A1 3553/4885TSHR 3371/4885TDP1 2808/4885 |
| US-10682419-B2 | Prodrugs of peptide epoxy ketone protease inhibitors | PREP, VIP, PEPD | ALDH1A1 1285/4885TSHR 3808/4885TDP1 2375/4885 |
| US-20210163526-A9 | Multi-Functional Chemical Agents, and the Method for Protein Modification | FN1, LCP1, NPM1 | ALDH1A1 3553/4885TSHR 3371/4885TDP1 2808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.