Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698672 | 0.79 | LMNA (0.36) | MEN1LMNAMAPTKMT2A | |
| SCHEMBL20206762 | 0.68 | — | — | |
| SCHEMBL9999112 | 0.68 | — | — | |
| SCHEMBL774689 | 0.64 | — | — | |
| SCHEMBL6285473 | 0.60 | — | — | |
| SCHEMBL7050607 | 0.60 | — | — | |
| SCHEMBL8402261 | 0.58 | NOS3 (0.35) | — | |
| SCHEMBL13469214 | 0.58 | — | — | |
| SCHEMBL1509853 | 0.57 | — | — | |
| SCHEMBL9612274 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |