Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 17/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206765 | 0.88 | DUT (0.50) | DUTCRBNDDB1POLBKMT2A | |
| SCHEMBL21315541 | 0.88 | DUT (0.71) | DUT | |
| SCHEMBL20206860 | 0.88 | DUT (0.71) | DUT | |
| SCHEMBL20206935 | 0.83 | DUT (0.50) | DUTCRBNDDB1POLBKMT2A | |
| SCHEMBL20201493 | 0.82 | DUT (0.76) | DUT | |
| SCHEMBL15865030 | 0.80 | DUT (0.70) | DUT | |
| SCHEMBL15865033 | 0.80 | DUT (0.70) | DUT | |
| SCHEMBL21325371 | 0.80 | DUT (0.67) | DUT | |
| SCHEMBL21315523 | 0.80 | DUT (0.67) | DUT | |
| SCHEMBL20190490 | 0.80 | DUT (0.67) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |