Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 17/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206766 | 0.88 | DUT (0.54) | DUTCRBNDDB1POLBKMT2A | |
| SCHEMBL20190490 | 0.85 | DUT (0.67) | DUT | |
| SCHEMBL21315523 | 0.85 | DUT (0.67) | DUT | |
| SCHEMBL21325371 | 0.85 | DUT (0.67) | DUT | |
| SCHEMBL20206994 | 0.84 | DUT (0.46) | DUTPOLBKMT2A | |
| SCHEMBL20201701 | 0.84 | DUT (0.60) | DUT | |
| SCHEMBL20207748 | 0.84 | DUT (0.60) | DUT | |
| SCHEMBL20201492 | 0.83 | DUT (0.70) | DUT | |
| SCHEMBL20206934 | 0.82 | DUT (0.45) | DUTPOLBKMT2A | |
| SCHEMBL20206992 | 0.82 | DUT (0.46) | DUTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |