Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 6/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 3/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207097 | 0.86 | CAMK2D (0.71) | CAMK2DKCNH2 | |
| SCHEMBL20186381 | 0.86 | CAMK2D (0.65) | CAMK2DKCNH2CAMKK1CAMKK2 | |
| SCHEMBL20186664 | 0.86 | CAMK2D (0.49) | CAMK2DKCNH2CAMKK1CAMKK2PIK3CD | |
| SCHEMBL20186380 | 0.86 | CAMK2D (0.65) | CAMK2DKCNH2CAMKK1CAMKK2 | |
| SCHEMBL20186661 | 0.86 | CAMK2D (0.49) | CAMK2DKCNH2CAMKK1CAMKK2PIK3CD | |
| SCHEMBL20186165 | 0.86 | CAMK2D (0.55) | CAMK2DKCNH2CAMKK1CAMKK2 | |
| SCHEMBL20225439 | 0.84 | CAMK2D (0.47) | CAMK2DKCNH2CAMKK1CAMKK2MAPT | |
| SCHEMBL22923501 | 0.84 | CAMK2D (0.47) | CAMK2DKCNH2CAMKK1CAMKK2MAPT | |
| SCHEMBL20186179 | 0.84 | CAMK2D (0.55) | CAMK2DKCNH2CAMKK1CAMKK2MEN1 | |
| SCHEMBL20186411 | 0.83 | CAMK2D (0.64) | CAMK2DKCNH2CAMKK1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148457-A1 | FUSED HETEROCYCLIC COMPOUNDS AS CAM KINASE INHIBITORS | GILEAD SCIENCES, INC. | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148457-A1 | FUSED HETEROCYCLIC COMPOUNDS AS CAM KINASE INHIBITORS | CAMK1, CAMKK1, CAMK1D | CAMK2D 6/4885KCNH2 388/4885CAMKK1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.