CAMK1

Calcium/calmodulin-dependent protein kinase type 1 · Q14012 · CAMK1 on Sugi Atlas →

10,570 patent compounds predicted against CAMK1, 8,244 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL546436 SCHEMBL546436 1.00 4/20
SCHEMBL147422 SCHEMBL147422 0.66 4/20
SCHEMBL144979 SCHEMBL144979 0.56 4/20
SCHEMBL660382 SCHEMBL660382 0.49 4/20
SCHEMBL232042 SCHEMBL232042 1.00 3/20
SCHEMBL146734 SCHEMBL146734 0.67 3/20
SCHEMBL144651 SCHEMBL144651 0.67 3/20
SCHEMBL146677 SCHEMBL146677 0.67 3/20
SCHEMBL144378 SCHEMBL144378 0.66 3/20
SCHEMBL142020 SCHEMBL142020 0.65 3/20
SCHEMBL148704 SCHEMBL148704 0.62 3/20
SCHEMBL147730 SCHEMBL147730 0.61 3/20
SCHEMBL148478 SCHEMBL148478 0.61 3/20
SCHEMBL144118 SCHEMBL144118 0.61 3/20
SCHEMBL144615 SCHEMBL144615 0.61 3/20
SCHEMBL147715 SCHEMBL147715 0.61 3/20
SCHEMBL143818 SCHEMBL143818 0.61 3/20
SCHEMBL143827 SCHEMBL143827 0.59 3/20
SCHEMBL145924 SCHEMBL145924 0.59 3/20
SCHEMBL144183 SCHEMBL144183 0.58 3/20

Clinical trials — most relevant to CAMK1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
COMS for Chronic Ulcers Treatment PHASE4RECRUITING
Multimodal Versus Opioid aNalgesia in carDiAc Surgery PHASE4COMPLETED
Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity PHASE4COMPLETED
Lithium for Prevention of Cognitive Declining in Mood Illnesses PHASE4NOT_YET_RECRUITING
Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients PHASE3ACTIVE_NOT_RECRUITING
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus PHASE3UNKNOWN
Evaluate Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients PHASE3COMPLETED
The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients PHASE1/PHASE2WITHDRAWN
Anti-Estrogens - A Potential Treatment for Bipolar Affective Disorder in Women? PHASE2COMPLETED
Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease PHASE2COMPLETED
Autologous Cytokine Induced Killer Cells (CIK) for Chronic Myeloid Leukemia (CML) Patients on Standard Drug Therapy PHASE2COMPLETED
Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction PHASE2ACTIVE_NOT_RECRUITING
Calcium Channel Blockade in Primary Aldosteronism PHASE2COMPLETED
EDTA Eye Drops Compared to Abreva for Herpes Simplex Virus Eruptions PHASE2COMPLETED
Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients PHASE1COMPLETED
Bioequivalence Study of Tacrolimus in Healthy Volunteers PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy EARLY_PHASE1RECRUITING
Epithelioid Haemangioendothelioma Observational Study nanRECRUITING
Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia nanRECRUITING
Role of Nitric Oxide in Diabetic Patients With Erectile Dysfunction nanCOMPLETED
Ischemic Preconditioning to Prevent Acute Kidney Injury nanCOMPLETED
NTRK 1,2,3 Rearrangements in Patients With Solid Tumors nanACTIVE_NOT_RECRUITING
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life nanCOMPLETED
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory nanCOMPLETED
Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure nanUNKNOWN
Assessing Bone Calcium Content in Children With Kidney Disease Treated With Two Different Medicines nanUNKNOWN
Evaluation of Vasopressin in the Vessels of Ovarian Neoplasms nanCOMPLETED
Urine Concentration of S100B in Extremely Premature Infants nanCOMPLETED
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a CAMK1 binder may also engage these)

ProteinNameSimilarity
Q91YS8 1.000 Q91YS8 →
Q63450 1.000 Q63450 →
PNCK Calcium/calmodulin-dependent protein kinase type 1B 0.994 landscape →
CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 0.994 landscape →
Q9QYK9 0.989 Q9QYK9 →
O70150 0.988 O70150 →
Q8BW96 0.988 Q8BW96 →
RPS6KA1 Ribosomal protein S6 kinase alpha-1 0.987 landscape →
Q9TXJ0 0.987 Q9TXJ0 →
W0LYS5 0.986 W0LYS5 →
A8X6H4 0.986 A8X6H4 →
Q6PFQ0 0.985 Q6PFQ0 →
Q54SJ5 0.983 Q54SJ5 →
Q869W6 0.982 Q869W6 →
Q6GLS4 0.981 Q6GLS4 →
Q9FMP5 0.981 Q9FMP5 →
Q5R4K3 0.981 Q5R4K3 →
DAPK2 Death-associated protein kinase 2 0.981 landscape →
Q8VDF3 0.980 Q8VDF3 →
RPS6KA3 Ribosomal protein S6 kinase alpha-3 0.980 landscape →
P13234 0.980 P13234 →
Q6U1I9 0.979 Q6U1I9 →
P18654 0.979 P18654 →
P18652 0.979 P18652 →
RPS6KA5 Ribosomal protein S6 kinase alpha-5 0.979 landscape →
RPS6KA2 Ribosomal protein S6 kinase alpha-2 0.979 landscape →
Q3E9C0 0.979 Q3E9C0 →
Q63531 0.979 Q63531 →
PRKCA Protein kinase C alpha type 0.979 landscape →
Q9SZM3 0.979 Q9SZM3 →