Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206957 | 0.87 | TP53 (0.44) | TP53CA1CA2 | |
| SCHEMBL5616728 | 0.71 | — | — | |
| SCHEMBL277730 | 0.71 | CA2 (0.38) | METAP1TP53CA12CA1CA2 | |
| SCHEMBL1908742 | 0.70 | — | — | |
| SCHEMBL30190155 | 0.70 | — | — | |
| SCHEMBL10016041 | 0.70 | — | — | |
| SCHEMBL2234132 | 0.70 | METAP1 (0.35) | METAP1TP53CA12CA1CA2 | |
| SCHEMBL1704349 | 0.69 | CA12 (0.33) | TP53CA12CA1CA2CA7 | |
| SCHEMBL28324318 | 0.69 | METAP1 (0.39) | METAP1TP53CA12CA1CA2 | |
| SCHEMBL598768 | 0.67 | TSHR (0.44) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |