Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207632 | 0.87 | METAP1 (0.35) | TP53CA1CA2 | |
| SCHEMBL8845642 | 0.85 | TP53 (0.43) | TP53OPRM1ACE2FDPSCA2 | |
| SCHEMBL28840440 | 0.73 | TP53 (0.38) | TP53ACE2ADH1BADH1CADH1A | |
| SCHEMBL9662687 | 0.73 | TP53 (0.56) | TP53OPRM1ACE2CA1ADH1B | |
| SCHEMBL750216 | 0.71 | OPRM1 (0.52) | TP53OPRM1ACE2CA1ADH1B | |
| SCHEMBL17676570 | 0.71 | TP53 (0.54) | TP53OPRM1ACE2CA1ADH1B | |
| SCHEMBL25991296 | 0.71 | TP53 (0.54) | TP53OPRM1ACE2CA1ADH1B | |
| SCHEMBL17424122 | 0.71 | TP53 (0.54) | TP53OPRM1ACE2CA1ADH1B | |
| SCHEMBL20376269 | 0.71 | TP53 (0.43) | TP53OPRM1CA1FDPSCA2 | |
| SCHEMBL20204682 | 0.70 | TP53 (0.46) | TP53OPRM1CA1FDPSCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |