Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15858992 | 0.84 | USP2 (0.49) | USP2TSHRNPC1ACACBDRD2 | |
| SCHEMBL14764488 | 0.83 | CYP2A6 (0.46) | NPC1ACACBMEN1CYP1A2CYP2C9 | |
| SCHEMBL5961837 | 0.83 | NPC1 (0.46) | TSHRNPC1ACACBDRD2DRD4 | |
| SCHEMBL2231003 | 0.82 | TSHR (0.50) | USP2TSHRNPC1DRD2DRD4 | |
| SCHEMBL29690404 | 0.78 | USP2 (0.47) | USP2TSHRNPC1DRD2DRD4 | |
| SCHEMBL18295367 | 0.78 | SCN4A (0.52) | USP2TSHRDRD2DRD4DRD3 | |
| SCHEMBL19121278 | 0.78 | USP2 (0.47) | USP2TSHRNPC1DRD2DRD4 | |
| SCHEMBL14570065 | 0.78 | LMNA (0.67) | USP2TSHRNPC1WDR5LMNA | |
| SCHEMBL9479823 | 0.78 | SCN4A (0.52) | USP2TSHRDRD2DRD4DRD3 | |
| SCHEMBL9123017 | 0.78 | USP2 (0.47) | USP2TSHRNPC1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |