SCHEMBL5961837

SCHEMBL5961837

CC(F)COc1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.46
ACACB O00763 1/20 0.43
TSHR P16473 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAOB P27338 2/20 0.41
APP P05067 1/20 0.41
LMNA P02545 1/20 0.41
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12306453 0.84 MAPT (0.47) NPC1TSHRCYP1A2CYP2D6CYP2C19
SCHEMBL20207652 0.83 USP2 (0.47) NPC1ACACBTSHRCYP1A2CYP2D6
SCHEMBL6273026 0.81 LMNA (0.64) NPC1TSHRLMNA
SCHEMBL8909086 0.81 MAOB (0.46) TSHRCYP1A2CYP2D6MAOBLMNA
SCHEMBL1835550 0.81 LMNA (0.64) NPC1TSHRLMNA
SCHEMBL1840653 0.81 LMNA (0.64) NPC1TSHRLMNA
SCHEMBL14123467 0.79 TSHR (0.42) NPC1TSHRCYP1A2CYP2D6CYP2C19
SCHEMBL9721664 0.78 TSHR (0.40) NPC1TSHRCYP1A2CYP2D6CYP2C19
SCHEMBL5662052 0.78 TSHR (0.40) NPC1TSHRCYP1A2CYP2D6CYP2C19
SCHEMBL14227156 0.78 CASR (0.44) NPC1TSHRCYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7074523-B2 Lithium secondary battery HITACHI, LTD. (JP) 2006-07-11 US disclosed
US-20040106039-A1 nonaqueous electrolytic solution containing a compound that is oxidized at a voltage > a charge end voltage of the battery and a compound which inhibits reactions at voltages < the charge end voltage ARAI JUICHI (JP) 2004-06-03 US disclosed
US-20030003370-A1 Nonaqueous electrolytic solution containing a compound which is oxidized at a voltage higher than a charge end voltage of the lithium secondary battery and a compound which inhibits reactions at voltages lower than said charge end voltage. HITACHI, LTD. (JP) 2003-01-02 US disclosed
EP-1258939-A2 Lithium secondary battery Hitachi, Ltd. (JP) 2002-11-20 EP disclosed