Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.79 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SAT1 | P21673 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21574012 | 1.00 | SIGMAR1 (0.79) | SIGMAR1EPHX1MAPTCYP1A2KDM5A | |
| SCHEMBL22519336 | 1.00 | SIGMAR1 (0.79) | SIGMAR1EPHX1MAPTCYP1A2KDM5A | |
| SCHEMBL6962219 | 0.97 | — | — | |
| SCHEMBL22697176 | 0.91 | SIGMAR1 (0.88) | SIGMAR1EPHX1MAPTCYP1A2KDM5A | |
| SCHEMBL19631563 | 0.91 | SIGMAR1 (0.88) | SIGMAR1EPHX1MAPTCYP1A2KDM5A | |
| SCHEMBL920031 | 0.90 | — | — | |
| SCHEMBL8092983 | 0.89 | SIGMAR1 (1.00) | SIGMAR1EPHX1MAPTCYP1A2KDM5A | |
| SCHEMBL6969290 | 0.88 | SIGMAR1 (0.91) | SIGMAR1EPHX1MAPTCYP1A2KDM5A | |
| SCHEMBL6975263 | 0.86 | SIGMAR1 (0.96) | SIGMAR1EPHX1MAPTCYP1A2KDM5A | |
| SCHEMBL26431397 | 0.86 | SIGMAR1 (0.96) | SIGMAR1EPHX1MAPTCYP1A2KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |