Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD2 | P13995 | 9/20 | 0.36 |
| ▸ | CCR4 | P51679 | 7/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | MTHFD1 | P11586 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208614 | 0.86 | MTHFD1 (0.39) | MTHFD2ERN1MTHFD1 | |
| Hydrochloric Acid SCHEMBL21354118 | 0.85 | MTHFD1 (0.38) | MTHFD2ERN1MTHFD1 | |
| SCHEMBL31535444 | 0.81 | MTHFD1 (0.30) | MTHFD2MTHFD1 | |
| SCHEMBL31535176 | 0.81 | MTHFD1 (0.30) | MTHFD2MTHFD1 | |
| SCHEMBL20209030 | 0.81 | MTHFD2 (0.51) | MTHFD2CCR4ERN1MTHFD1 | |
| Hydrochloric Acid SCHEMBL21354084 | 0.80 | MTHFD2 (0.50) | MTHFD2CCR4ERN1MTHFD1 | |
| SCHEMBL31535487 | 0.80 | ERN1 (0.32) | ERN1 | |
| SCHEMBL20209031 | 0.77 | ERN1 (0.48) | ERN1 | |
| Sulfuric Acid SCHEMBL31535353 | 0.74 | ERN1 (0.47) | ERN1 | |
| SCHEMBL31535274 | 0.72 | MTHFD1 (0.33) | MTHFD2MTHFD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3546463-B1 | SULFONAMIDE DERIVATIVE HAVING COUMARIN SKELETON | DAIICHI SANKYO CO LTD (JP) | 2022-12-07 | — | — | EP | disclosed |
| EP-3546463-A1 | SULFONAMIDE DERIVATIVE HAVING COUMARIN SKELETON | Daiichi Sankyo Co., Ltd. (JP) | 2019-10-02 | — | — | EP | disclosed |
| WO-2018097162-A1 | SULFONAMIDE DERIVATIVE HAVING COUMARIN SKELETON | 第一三共株式会社 | 2018-05-31 | — | — | WO | disclosed |