Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208934 | 0.92 | MEN1 (0.33) | CYP1A2CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL20208630 | 0.86 | P2RX4 (0.30) | — | |
| SCHEMBL22145841 | 0.84 | PTGER4 (0.34) | CYP1A2CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL20208937 | 0.84 | MAPT (0.32) | MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL20208949 | 0.82 | TSHR (0.32) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL20208650 | 0.78 | — | — | |
| SCHEMBL20208970 | 0.78 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL20208945 | 0.78 | — | — | |
| SCHEMBL20208933 | 0.77 | KDM4E (0.30) | KDM4E | |
| SCHEMBL20208636 | 0.77 | ALDH1A1 (0.38) | MEN1KMT2ALMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018095839-A1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |