Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208937 | 0.88 | MAPT (0.32) | HSD17B10RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22145789 | 0.86 | NPY5R (0.34) | TSHRHSD17B10MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL20208630 | 0.85 | P2RX4 (0.30) | — | |
| SCHEMBL20208934 | 0.83 | MEN1 (0.33) | TSHRHSD17B10ALDH1A1LMNAMEN1 | |
| SCHEMBL20208941 | 0.82 | CYP1A2 (0.35) | TSHRHSD17B10MAPK1TP53MAPT | |
| SCHEMBL20209403 | 0.81 | — | — | |
| SCHEMBL20208636 | 0.79 | ALDH1A1 (0.38) | HSD17B10MAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL20208650 | 0.79 | — | — | |
| SCHEMBL20208970 | 0.78 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL20208946 | 0.78 | ALDH1A1 (0.34) | TSHRHSD17B10MAPK1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018095839-A1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |