Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CD38 | P28907 | 13/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20209088 | 0.85 | CD38 (0.40) | CD38 | |
| SCHEMBL29625002 | 0.85 | CD38 (0.40) | CD38 | |
| SCHEMBL20209150 | 0.74 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL20935100 | 0.72 | CYP19A1 (0.39) | CYP19A1CYP11B1CYP11B2ADRB2ADRB1 | |
| SCHEMBL20209076 | 0.71 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL20935311 | 0.69 | CYP19A1 (0.38) | CYP19A1CYP11B1CYP11B2ADRB2ADRB1 | |
| SCHEMBL20208921 | 0.68 | ALDH1A1 (0.41) | MAPK1 | |
| SCHEMBL23111910 | 0.67 | MAPT (0.41) | CD38 | |
| SCHEMBL25934515 | 0.66 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL20187673 | 0.66 | NPSR1 (0.42) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096325-A1 | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | Enterprise Therapeutics Limited (GB) | 2018-05-31 | — | — | WO | disclosed |