Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 8/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208921 | 0.83 | ALDH1A1 (0.41) | MAPK1RIPK1DYRK1AJAK3 | |
| SCHEMBL20209076 | 0.82 | MAPK1 (0.37) | MAPK1RIPK1 | |
| SCHEMBL25934515 | 0.77 | MAPK1 (0.50) | MAPK1RIPK1DYRK1A | |
| SCHEMBL20187673 | 0.77 | NPSR1 (0.42) | MAPK1DYRK1A | |
| SCHEMBL20209080 | 0.74 | CYP19A1 (0.37) | MAPK1 | |
| SCHEMBL25934516 | 0.71 | MAPK1 (0.44) | MAPK1RIPK1DYRK1A | |
| SCHEMBL25934519 | 0.70 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL20208919 | 0.70 | MAP4K1 (0.36) | — | |
| SCHEMBL25934521 | 0.69 | CD38 (0.33) | MAPK1DYRK1A | |
| SCHEMBL20209088 | 0.68 | CD38 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096325-A1 | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | Enterprise Therapeutics Limited (GB) | 2018-05-31 | — | — | WO | disclosed |