Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21578710 | 0.93 | ATM (0.38) | ATMKDM4EL3MBTL1ALDH1A1FAAH | |
| SCHEMBL20208726 | 0.91 | KDM4E (0.41) | ATMKDM4EL3MBTL1ALDH1A1EDNRB | |
| SCHEMBL19035968 | 0.88 | ATM (0.37) | ATMKDM4EL3MBTL1ALDH1A1FAAH | |
| SCHEMBL22958735 | 0.87 | EDNRB (0.37) | ATMKDM4EL3MBTL1ALDH1A1EDNRB | |
| SCHEMBL19035996 | 0.87 | ATM (0.36) | ATMKDM4EL3MBTL1ALDH1A1FAAH | |
| SCHEMBL20208601 | 0.87 | L3MBTL1 (0.39) | ATMKDM4EL3MBTL1ALDH1A1HTT | |
| SCHEMBL20208602 | 0.86 | L3MBTL1 (0.41) | ATMKDM4EL3MBTL1ALDH1A1HTT | |
| SCHEMBL23936688 | 0.86 | L3MBTL1 (0.43) | ATMKDM4EL3MBTL1ALDH1A1FAAH | |
| SCHEMBL20208724 | 0.86 | KDM4E (0.33) | ATMKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL19009395 | 0.86 | ATM (0.35) | ATMKDM4EL3MBTL1ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018095839-A1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |