Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208602 | 0.98 | L3MBTL1 (0.41) | L3MBTL1KDM4EATMHDAC4KMT2A | |
| SCHEMBL20208610 | 0.88 | KDM4E (0.38) | L3MBTL1KDM4EATMKMT2AIL1R1 | |
| SCHEMBL22958706 | 0.88 | L3MBTL1 (0.40) | L3MBTL1KDM4EATMHDAC4KMT2A | |
| SCHEMBL22958727 | 0.87 | L3MBTL1 (0.42) | L3MBTL1KDM4EATMHDAC4KMT2A | |
| SCHEMBL20209199 | 0.87 | ATM (0.38) | L3MBTL1KDM4EATMALDH1A1HTT | |
| SCHEMBL20208726 | 0.87 | KDM4E (0.41) | L3MBTL1KDM4EATMALDH1A1 | |
| SCHEMBL22958792 | 0.86 | L3MBTL1 (0.45) | L3MBTL1KDM4EATMHDAC4KMT2A | |
| SCHEMBL25636733 | 0.86 | L3MBTL1 (0.40) | L3MBTL1KDM4EATMHDAC4KMT2A | |
| SCHEMBL19035998 | 0.86 | ATM (0.35) | L3MBTL1KDM4EATMHDAC4ALDH1A1 | |
| SCHEMBL19036003 | 0.85 | EDNRB (0.35) | L3MBTL1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018095839-A1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |