SCHEMBL20209470

SCHEMBL20209470

c1ccc2oc(-c3ccc(N(c4ccc(-c5cc6ccccc6o5)cc4)c4ccc5cc(N(c6ccc(-c7cc8ccccc8o7)cc6)c6ccc(-c7cc8ccccc8o7)cc6)ccc5c4)cc3)cc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.58
ALOX5 P09917 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
NFKB1 P19838 1/20 0.48
NPY1R P25929 1/20 0.48
RAB9A P51151 1/20 0.48
NFKB2 Q00653 1/20 0.48
KMT2A Q03164 1/20 0.48
RELA Q04206 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MAOA P21397 3/20 0.47
PTPRC P08575 1/20 0.47
PTPN1 P18031 1/20 0.47
APP P05067 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24369502 0.97 MAOB (0.55) MAOBALOX5CA1CA2CA9
SCHEMBL13475658 0.93 MAOB (0.66) MAOBALOX5CA1CA2CA9
SCHEMBL20209465 0.92 ALOX5 (0.51) MAOBALOX5CA1CA2CA9
SCHEMBL24368355 0.92 MAOB (0.64) MAOBALOX5CA1CA2CA9
SCHEMBL24368733 0.92 MAOB (0.64) MAOBALOX5CA1CA2CA9
SCHEMBL24368356 0.92 MAOB (0.64) MAOBALOX5CA1CA2CA9
SCHEMBL24368740 0.91 MAOB (0.55) MAOBALOX5CA1CA2CA9
SCHEMBL24368490 0.91 MAOB (0.55) MAOBALOX5CA1CA2CA9
SCHEMBL24368491 0.91 MAOB (0.55) MAOBALOX5CA1CA2CA9
SCHEMBL24368407 0.91 MAOB (0.55) MAOBALOX5CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11239426-B2 Electroactive compounds LG CHEM, LTD. 2022-02-01 US disclosed
WO-2018097937-A1 ELECTROACTIVE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2018-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11239426-B2 Electroactive compounds KCNN2, HCN2, KCNN3 MAOB 122/4885ALOX5 752/4885CA1 629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.