SCHEMBL20209975

SCHEMBL20209975

Fc1cc(COc2c(F)cc(-c3ccc(C4CCCCC4)cc3)cc2F)cc(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 3/20 0.40
F10 P00742 1/20 0.39
CYP3A4 P08684 2/20 0.36
CYP2C9 P11712 1/20 0.36
APP P05067 1/20 0.36
FEN1 P39748 4/20 0.35
ALOX5AP P20292 2/20 0.35
HSP90AA1 P07900 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HRH3 Q9Y5N1 2/20 0.35
MAOB P27338 1/20 0.34
PTGDR Q13258 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
KCNH2 Q12809 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19711842 0.96 FFAR4 (0.40) FFAR4F10FEN1ALOX5APMAOB
SCHEMBL19097979 0.88 FFAR4 (0.41) FFAR4F10FEN1ALOX5APHRH3
SCHEMBL19097887 0.86 CYP3A4 (0.38) FFAR4CYP3A4CYP2C9APPFEN1
SCHEMBL19082834 0.85 FFAR4 (0.39) FFAR4F10CYP3A4CYP2C9HRH3
SCHEMBL16039133 0.83 FFAR4 (0.42) FFAR4F10CYP3A4CYP2C9MAPT
SCHEMBL16038940 0.83 FFAR4 (0.42) FFAR4F10CYP3A4CYP2C9MAPT
SCHEMBL18464121 0.83 HSP90AA1 (0.46) CYP3A4CYP2C9APPHSP90AA1GAA
SCHEMBL19711840 0.82 FEN1 (0.40) FFAR4FEN1ALOX5APMAOB
SCHEMBL20209635 0.82 PRKAG1 (0.40) FFAR4F10FEN1ALOX5APHRH3
SCHEMBL19711838 0.82 PRMT5 (0.40) F10FEN1ALOX5APTDP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed