SCHEMBL20209635

SCHEMBL20209635

Fc1cc(COc2c(F)cc(-c3ccc(C4CCCCO4)cc3)cc2F)cc(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRKAG1 P54619 11/20 0.40
PRKAA1 Q13131 11/20 0.40
PRKAB1 Q9Y478 11/20 0.40
PRKAA2 P54646 10/20 0.40
PRKAB2 O43741 8/20 0.39
PRKAG3 Q9UGI9 8/20 0.39
PRKAG2 Q9UGJ0 8/20 0.39
KCNH2 Q12809 2/20 0.38
HRH3 Q9Y5N1 2/20 0.38
F10 P00742 1/20 0.36
FFAR4 Q5NUL3 2/20 0.35
FEN1 P39748 2/20 0.31
MAOB P27338 1/20 0.31
ALOX5AP P20292 1/20 0.31
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19098118 0.88 PRKAG1 (0.38) PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2
SCHEMBL20209766 0.85 CYP11B1 (0.37) F10FFAR4MAOB
SCHEMBL19097884 0.82 F10 (0.35) HRH3F10FFAR4MAOB
SCHEMBL20209975 0.82 FFAR4 (0.40) KCNH2HRH3F10FFAR4FEN1
SCHEMBL19478727 0.82 KCNH2 (0.41) PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2
SCHEMBL19711842 0.81 FFAR4 (0.40) F10FFAR4FEN1MAOBALOX5AP
SCHEMBL19082844 0.81 F10 (0.34) F10FFAR4MAOB
SCHEMBL19082862 0.79 FASN (0.41) F10FFAR4MAOB
SCHEMBL21910588 0.78 KCNH2 (0.44) PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2
SCHEMBL19097885 0.77 F10 (0.32) F10FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed