SCHEMBL20209999

SCHEMBL20209999

Cc1cc(C)c(Nc2c(C)c(C)c(C)c(C)c2C)c(C)c1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502929 0.89 RAPGEF4 (1.00) RAPGEF4
SCHEMBL14168981 0.77 RAPGEF4 (0.75) RAPGEF4
SCHEMBL7943275 0.76 RAPGEF4 (0.37) RAPGEF4
SCHEMBL15888883 0.75 RAPGEF4 (0.73) RAPGEF4
SCHEMBL12018925 0.74 RAPGEF4 (0.47) RAPGEF4
SCHEMBL1551822 0.73 RAPGEF4 (0.59) RAPGEF4
SCHEMBL28951 0.73 RAPGEF4 (0.59) RAPGEF4
SCHEMBL29196013 0.72 RAPGEF4 (0.52) RAPGEF4
SCHEMBL13776396 0.72 RAPGEF4 (0.73) RAPGEF4
SCHEMBL14347189 0.72 RAPGEF4 (0.58) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022034916-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2022-02-17 WO disclosed
EP-3544984-B1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
WO-2018095888-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 WO disclosed