SCHEMBL29196013

SCHEMBL29196013

Cc1cc(C)c(Nc2c(C)cc(C)c(C)c2C)c(C)c1C

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29196018 0.81 RAPGEF4 (0.50) RAPGEF4
SCHEMBL436385 0.80 RAPGEF4 (0.38) RAPGEF4
SCHEMBL18183247 0.79 RAPGEF4 (0.45) RAPGEF4
SCHEMBL18183245 0.74 CYP3A4 (0.41) RAPGEF4
SCHEMBL120101 0.73 TSHR (0.39) RAPGEF4
SCHEMBL21341450 0.72 RAPGEF4 (0.32) RAPGEF4
SCHEMBL22436242 0.72 RAPGEF4 (0.42) RAPGEF4
SCHEMBL20209999 0.72 RAPGEF4 (0.79) RAPGEF4
SCHEMBL21608255 0.71 ALDH1A1 (0.33) RAPGEF4
SCHEMBL13059571 0.71 ALDH1A1 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed