SCHEMBL20210567

SCHEMBL20210567

COCCC(=O)OCC(C)C

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.42
MAPT P10636 1/20 0.40
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EPHX2 P34913 1/20 0.36
PRKCA P17252 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36
PRKCD Q05655 1/20 0.36
ENPP2 Q13822 4/20 0.36
ADRA2A P08913 1/20 0.35
ADRA1A P35348 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898097 0.88 POLB (0.38) TSHRMAPTPOLBGAAALDH1A1
SCHEMBL10087841 0.88 POLB (0.38) TSHRMAPTPOLBGAAALDH1A1
SCHEMBL10087836 0.88 POLB (0.38) TSHRMAPTPOLBGAAALDH1A1
SCHEMBL10087835 0.88 POLB (0.38) TSHRMAPTPOLBGAAALDH1A1
SCHEMBL20210621 0.88 MAPT (0.46) TSHRMAPTALDH1A1TDP1EPHX2
SCHEMBL20210699 0.86 MAPT (0.49) TSHRMAPTALDH1A1TDP1EPHX2
SCHEMBL28146460 0.85 TSHR (0.40) TSHRMAPTPOLBGAAALDH1A1
SCHEMBL5481945 0.85 MAPT (0.56) TSHRMAPTALDH1A1TDP1PRKCA
SCHEMBL20210444 0.84 ALDH1A1 (0.52) MAPTALDH1A1EPHX2PRKCAPRKCE
SCHEMBL334176 0.84 TSHR (0.50) TSHRMAPTPOLBGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108148153-B Solid catalyst and method for preparing propylene polymer or copolymer using the same 韩华道达尔有限公司 2021-08-10 CN disclosed
US-10808048-B2 Process of manufacture of catalyst and propylene polymer that use this or copolymer for propylene polymerization HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2020-10-20 US disclosed
EP-3683243-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2020-07-22 EP disclosed
US-20180155461-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-07 US disclosed
EP-3330299-A1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION Hanwha Total Petrochemical Co., Ltd. (KR) 2018-06-06 EP disclosed