Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374809 | 0.74 | KDM4E (0.40) | KDM4EMTNR1AMTNR1BCA4LMNA | |
| SCHEMBL7973687 | 0.73 | MTNR1A (0.40) | KDM4EMTNR1AMTNR1BCA4LMNA | |
| SCHEMBL9296320 | 0.69 | KDM4E (0.47) | KDM4EMTNR1AMTNR1BCA4LMNA | |
| SCHEMBL22545038 | 0.68 | LMNA (0.47) | MTNR1AMTNR1BLMNACYP2C9CYP2C19 | |
| SCHEMBL18328138 | 0.68 | PDE2A (0.58) | PDE2AKDM4ELMNAGAAADRA2A | |
| SCHEMBL22042123 | 0.68 | PDE2A (0.58) | PDE2AKDM4ELMNAGAAADRA2A | |
| SCHEMBL13983512 | 0.68 | PDE2A (0.58) | PDE2AKDM4ELMNAGAAADRA2A | |
| SCHEMBL5325563 | 0.68 | MTNR1A (0.39) | KDM4EMTNR1AMTNR1BCA4LMNA | |
| SCHEMBL1453272 | 0.68 | CA4 (0.48) | KDM4EMTNR1AMTNR1BCA4LMNA | |
| SCHEMBL12394 | 0.68 | KMT2A (0.54) | KDM4EMTNR1AMTNR1BCA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018102006-A1 | COMPOUNDS FOR THE INHIBITION OF INDOLEAMINE-2,3-DIOXYGENASE ACTIVITY AND USE THEREOF | ENSEMBLE THERAPEUTICS CORPORATION (US) | 2018-06-07 | — | — | WO | disclosed |