Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214711 | 0.78 | NPC1 (0.45) | RAB9ANPC1ATML3MBTL1KDM4E | |
| SCHEMBL12468767 | 0.74 | CTSD (0.69) | RAB9ANPC1KDM4EHSD17B10HPGD | |
| SCHEMBL6536150 | 0.73 | RAB9A (0.73) | RAB9ANPC1 | |
| SCHEMBL13527518 | 0.72 | HSD17B10 (0.62) | RAB9ANPC1KDM4EHSD17B10HPGD | |
| SCHEMBL20214224 | 0.72 | MAOB (0.58) | RAB9ANPC1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL20214231 | 0.69 | RAB9A (0.71) | RAB9ANPC1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL17339636 | 0.69 | HPGD (0.74) | RAB9AATML3MBTL1KDM4EHPGD | |
| SCHEMBL20214331 | 0.69 | RAB9A (0.51) | RAB9ANPC1HPGDALDH1A1TSHR | |
| SCHEMBL20214216 | 0.69 | HDAC3 (0.64) | RAB9ANPC1ATML3MBTL1MEN1 | |
| SCHEMBL5302217 | 0.69 | KDM4E (0.65) | RAB9ANPC1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200181175-A1 | BORONIC DERIVATIVES OF HYDROXAMATES AS ANTICANCER AGENTS | XAVIER UNIVERSITY OF LOUISIANA | 2020-06-11 | — | — | US | claimed |
| WO-2018102261-A2 | BORONIC DERIVATIVES HYDROXAMATES AS ANTICANCER AGENTS | XAVIER UNIVERSITY OF LOUISIANA (US) | 2018-06-07 | — | — | WO | claimed |
| US-11046715-B2 | Boronic derivatives of hydroxamates as anticancer agents | XAVIER UNIVERSITY OF LOUISIANA (US) | 2021-06-29 | — | — | US | disclosed |
| US-20200181175-A1 | BORONIC DERIVATIVES OF HYDROXAMATES AS ANTICANCER AGENTS | XAVIER UNIVERSITY OF LOUISIANA | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181175-A1 | BORONIC DERIVATIVES OF HYDROXAMATES AS ANTICANCER AGENTS | BCOR, BRDT, HDAC1 | RAB9A 3029/4885NPC1 801/4885ATM 1129/4885 |
| US-11046715-B2 | Boronic derivatives of hydroxamates as anticancer agents | BCOR, BRDT, HDAC1 | RAB9A 3029/4885NPC1 801/4885ATM 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.