Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.31 |
| ▸ | ADK | P55263 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214768 | 0.89 | TAS1R3 (0.35) | DNPH1TAS1R3TAS1R1P2RX3P2RX4 | |
| SCHEMBL21073932 | 0.89 | KDM4E (0.38) | DNPH1TAS1R3TAS1R1P2RX3P2RX4 | |
| SCHEMBL20214747 | 0.86 | TAS1R3 (0.33) | DNPH1TAS1R3TAS1R1IMPDH2 | |
| SCHEMBL20213829 | 0.81 | P2RY12 (0.36) | DNPH1P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL23228155 | 0.81 | P2RY12 (0.36) | DNPH1P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL19762769 | 0.80 | KDM4E (0.38) | DNPH1TAS1R3TAS1R1P2RY12KDM4E | |
| SCHEMBL25680037 | 0.80 | KDM4E (0.39) | DNPH1TAS1R3TAS1R1P2RX3P2RX4 | |
| SCHEMBL20214601 | 0.79 | DNPH1 (0.44) | DNPH1P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL21073930 | 0.79 | KDM4E (0.38) | TAS1R3TAS1R1P2RY12KDM4EIMPDH2 | |
| SCHEMBL22500175 | 0.79 | DNPH1 (0.40) | DNPH1TAS1R3TAS1R1P2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512861-A2 | CYCLIC DINUCLEOTIDES AS STING (STIMULATOR OF INTEFERON GENES) AGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018100558-A2 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-06-07 | — | — | WO | disclosed |