Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207638 | 0.93 | CA2 (0.52) | ZDHHC7HCAR2KEAP1NFE2L2CA2 | |
| SCHEMBL23744009 | 0.80 | HCAR2 (0.49) | HCAR2CA2GRIK1GRIK2GPR84 | |
| SCHEMBL18873517 | 0.78 | CA2 (0.50) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL18873711 | 0.78 | CA2 (0.50) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL18869115 | 0.78 | CA2 (0.50) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL21101871 | 0.78 | CA2 (0.43) | ZDHHC7CA2CA1GRIK1GRIK2 | |
| SCHEMBL8683284 | 0.77 | HCAR2 (0.56) | HCAR2KEAP1NFE2L2CA2CA1 | |
| SCHEMBL22005512 | 0.77 | ZDHHC7 (0.47) | ZDHHC7HCAR2KEAP1NFE2L2CA2 | |
| SCHEMBL18723159 | 0.77 | ZDHHC7 (0.47) | ZDHHC7HCAR2KEAP1NFE2L2CA2 | |
| SCHEMBL22005200 | 0.77 | ZDHHC7 (0.47) | ZDHHC7HCAR2KEAP1NFE2L2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988340-B2 | Compositions and methods for the treatment of multiple sclerosis | CELLIX BIO PRIVATE LIMITED (IN) | 2018-06-05 | — | — | US | disclosed |