Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17504764 | 0.86 | FOLH1 (0.58) | FOLH1GRM3NAALAD2 | |
| SCHEMBL19220635 | 0.86 | PLA2G2C (0.43) | FOLH1GRM3NAALAD2 | |
| SCHEMBL17504769 | 0.81 | PLA2G2C (0.46) | FOLH1GRM3NAALAD2 | |
| SCHEMBL17533765 | 0.77 | FOLH1 (0.54) | FOLH1GRM3NAALAD2 | |
| SCHEMBL17533513 | 0.76 | SLC1A1 (0.35) | — | |
| SCHEMBL8055987 | 0.75 | FOLH1 (0.65) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8052218 | 0.73 | FOLH1 (0.62) | FOLH1GRM3NAALAD2 | |
| SCHEMBL21805451 | 0.73 | CHRM1 (0.54) | FOLH1GRM3NAALAD2 | |
| SCHEMBL6381682 | 0.72 | FOLH1 (0.78) | FOLH1GRM3NAALAD2 | |
| SCHEMBL28633464 | 0.71 | FOLH1 (0.50) | FOLH1GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988407-B2 | Prodrugs of prostate specific membrane antigen (PSMA) inhibitor | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-06-05 | — | — | US | disclosed |